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Found 26 Enz. Inhib. hit(s) with all data for entry = 50033286
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116537(3-({3-[4-(Biphenyl-4-yloxy)-phenoxy]-propyl}-methy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116560(3-{Methyl-[3-(4-thiophen-3-ylmethyl-phenoxy)-propy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50342776(4-((3-(4-(biphenyl-4-yloxy)phenylamino)-6-azabicyc...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50251446(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50251500(4-(((2,2-dimethyl-3-(methyl(2-oxo-2-(4-phenoxyphen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50342777(4-((3-(4-(benzo[d]thiazol-2-yloxy)phenylamino)-6-a...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50125420(5-[2-(4-Benzyl-phenoxy)-ethyl]-5H-imidazo[4,5-c]py...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50251501(4-((methyl(2-(methyl(2-oxo-2-(4-phenoxyphenylamino...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116531(3-[4-(4-Benzyl-phenoxy)-butylamino]-propionic acid...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50251825(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50121023(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-ol | C...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50251387(2-(Methyl-{3-[methyl-(4-sulfamoyl-benzyl)-amino]-p...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50121008(CHEMBL114563 | N-{1-[2-(4-Benzyl-phenoxy)-ethyl]-p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50121005(CHEMBL115227 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pip...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116557(CHEMBL117455 | {[4-(4-Benzyl-phenoxy)-butyl]-methy...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116540(3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085266(4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116547(3-[2-(4-Benzyl-phenoxy)-ethylamino]-propionic acid...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50285633((R)-3-Benzyl-N-((S)-1-carboxy-ethyl)-succinamic ac...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50121013((S)-1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-2-c...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085258(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50116543(3-{Methyl-[3-(4-pyridin-3-ylmethyl-phenoxy)-propyl...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085254(1-[2-(4-Benzyl-2-chloro-phenoxy)-ethyl]-pyrrolidin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50285634((R)-1-((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085257(1-[2-(4-Phenylmethanesulfonyl-phenoxy)-ethyl]-pyrr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed