Compile Data Set for Download or QSAR
maximum 50k data
Found 87 Enz. Inhib. hit(s) with all data for entry = 50033120
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339877(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339880(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339881(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339882((S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-y...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339883((S)-1-ethyl-3-(1-(2-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339885(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50161517(6-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-hexan-1-on...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50161517(6-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-hexan-1-on...)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339887(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339890((S)-1-(1-(2-(4-chlorophenyl)pyrimidin-4-yl)piperid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339889((S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperi...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50:  36nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339892((S)-1-ethyl-3-(1-(2-p-tolylpyrimidin-4-yl)piperidi...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339894((S)-1-ethyl-3-(1-(2-(3-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339893((S)-1-ethyl-3-(1-(4-phenylpyrimidin-2-yl)piperidin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339895((S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339877(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  75nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339885(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  75nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339881(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  83nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339883((S)-1-ethyl-3-(1-(2-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50339880(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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