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Found 12 Enz. Inhib. hit(s) with all data for entry = 50033132
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340097(5-(4-(2-hydroxyethoxy)benzylidene)-2-thioxothiazol...)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340096(5-(3, 4-bis(2-hydroxyethoxy)benzylidene)-2-thioxot...)
Affinity DataIC50:  5.69E+6nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50092273((Z)-5-(2'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  9.55E+6nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.01E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50219502(4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...)
Affinity DataIC50:  1.04E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340094(1-(4-ethyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyr...)
Affinity DataIC50:  1.07E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340098(5-(4-hydroxy-3-methoxybenzylidene)-2-thioxothiazol...)
Affinity DataIC50:  1.11E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340095(1-(4-(4-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50:  1.23E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340091(1-(4-(2-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50:  1.63E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340092(1-(4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo...)
Affinity DataIC50:  2.01E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340093(1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50:  2.51E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed