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Found 12 Enz. Inhib. hit(s) with all data for entry = 4638
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM26198(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Affinity DataIC50:  4.5nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM26198(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Affinity DataIC50:  5.20nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50:  6.10nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM26198(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM26198(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Affinity DataIC50:  41nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50:  176nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  1.02E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  2.55E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of Luxembourg

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  8.06E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed