Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50033505
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346528(2,5-dihydro-1H-pyrrole-2-carboximidamide | CHEMBL1...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346520(CHEMBL1783072 | cyclobutanecarboximidamide)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346527(CHEMBL1783092 | pyrrolidine-2-carboximidamide)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346519(CHEMBL1783071 | cyclopropanecarboximidamide)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346521(CHEMBL1229853 | cyclopentanecarboximidamide)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346526(CHEMBL1783091 | tetrahydrothiophene-2-carboximidam...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346525(CHEMBL1783090 | tetrahydrofuran-2-carboximidamide)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346531(CHEMBL1783096 | azetidine-3-carboximidamide)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346523(CHEMBL1783074 | piperidine-3-carboximidamide)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346524(CHEMBL1783089 | piperidine-4-carboximidamide)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346522(CHEMBL1783073 | piperidine-2-carboximidamide)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  4.66E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataKd:  630nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed