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Found 22 Enz. Inhib. hit(s) with all data for entry = 50033383
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344203(5-Amino-3-[[3-(3-aminophenyl)-5-methyl-1H-pyrrol-2...)
Affinity DataIC50:  51nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344205(3-[[3-(3-Aminophenyl)-5-methyl-1H-pyrrol-2-yl]meth...)
Affinity DataIC50:  62nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344202(5-Amino-3-[[3-(4-aminophenyl)-5-methyl-1H-pyrrol-2...)
Affinity DataIC50:  68nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344201(3-[[3-[3-[(2-Aminoethyl)amino]phenyl]]-5-methyl-1H...)
Affinity DataIC50:  89nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344200(3-[[3-[4-[(2-Aminoethyl)amino]phenyl]]-5-methyl-1H...)
Affinity DataIC50:  149nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344204(3-[[3-(4-Aminophenyl)-5-methyl-1H-pyrrol-2-yl]meth...)
Affinity DataIC50:  368nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344198(3-[[4-[4-[(2-Aminoethyl)amino]phenyl]]-3,5-dimethy...)
Affinity DataIC50:  415nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344199(3-[[4-[3-[(2-Aminoethyl)amino]phenyl]]-3,5-dimethy...)
Affinity DataIC50:  605nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  850nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344216((Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,...)
Affinity DataIC50:  910nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344215(3-((2-ethyl-4-methyl-1H-imidazol-5-yl)methylene)in...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50227519(4-(6,7-dimethoxyquinazolin-4-ylamino)phenol | CHEM...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344213((E)-4-chloro-2-((2-(4-hydroxy-3-methoxyphenyl)-7-m...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344212(4-(6-bromoquinazolin-4-ylamino)phenol | CHEMBL1778...)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344211(CHEMBL1778713 | ethyl 4-(4-(4-chlorophenylamino)pt...)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344210(5-(2-oxoindolin-3-ylidene)-2-(p-tolylamino)thiazol...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM67668((6E)-6-[4-(4-hydroxyanilino)-1H-quinazolin-2-ylide...)
Affinity DataIC50:  4.24E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344208(2-(4-(4-chlorophenylamino)quinazolin-2-yl)phenol |...)
Affinity DataIC50:  6.46E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344207(4-(6-nitroquinazolin-4-ylamino)phenol | CHEMBL1778...)
Affinity DataIC50:  8.66E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344206(2,6-dimethyl-4-((2-(thiophen-2-yl)-1H-pyrrolo[2,3-...)
Affinity DataIC50:  9.29E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed