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Found 45 Enz. Inhib. hit(s) with all data for entry = 50033440
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345462(Allyl 8-Oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345463(2-Oxo-2-(propylthio)ethyl 8-Oxo-8H-acenaphtho[1,2-...)
Affinity DataIC50:  65nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50:  74nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345464(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 8-Oxo-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345466(Allyl 3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrr...)
Affinity DataIC50:  216nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345458(CHEMBL1784730 | Ethyl 3-(2-Hydroxyethylthio)-8-oxo...)
Affinity DataIC50:  320nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM4882((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...)
Affinity DataIC50:  334nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345470(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 3-(All...)
Affinity DataIC50:  424nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345455(CHEMBL1784727 | Ethyl 3-(Allylthio)-8-oxo-8H-acena...)
Affinity DataIC50:  485nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345468(2-Oxo-2-(propylthio)ethyl 3-(Allylthio)-8-oxo-8H-a...)
Affinity DataIC50:  577nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345457(CHEMBL1784729 | Ethyl 8-Oxo-3-(2-(pyrazin-2-yl)eth...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of VEGFR1 using poly(Glu-Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345452(3-(1-(5-Methyl-1,3-oxathiolan-5-yl)ethylthio)-8-ox...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345445(8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile |...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of FGFR3 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-Met expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1R expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345446(8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyrrole-9...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345447(3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345448(3-(Isopropylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345449(8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acenaphtho[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345450(3-(2-Hydroxyethylthio)-8-oxo-8H-acenaphtho[1,2-b]p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345451(3-(2-Methyltetrahydrofuran-3-ylthio)-8-oxo-8H-acen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345453(8-Oxo-3-(2-(thiazolidin-3-yl)ethylthio)-8H-acenaph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345454(CHEMBL1784726 | Ethyl 8-Oxo-3-(propylthio)-8H-acen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345456(CHEMBL1784728 | Ethyl 3-(Isopropylthio)-8-oxo-8H-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345459(CHEMBL1784731 | Ethyl 3-(2-Methyltetrahydrofuran-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345460(CHEMBL1784732 | Ethyl 3-(1-(5-Methyl-1,3-oxathiola...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345461(CHEMBL1784733 | Ethyl 8-Oxo-3-(2-(thiazolidin-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR4 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345465(Allyl 8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR2 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345467(2-Oxo-2-(propylthio)ethyl 8-Oxo-3-(propylthio)-8H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345469(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 8-Oxo-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RON expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphA2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Abl using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-Src expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR2 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RET expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRalpha using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRbeta using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345444(CHEMBL1784725 | Ethyl 8-oxo-8H-acenaphtho[1,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-kit expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed