Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50035849
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  1.30nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003747((+)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  6nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  8.70nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  11nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013968(2-(2-Amino-4,5-dichloro-phenyl)-N-methyl-N-(2-pyrr...)
Affinity DataKi:  11nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]bremazocine radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013966((2-Benzo[1,3]dioxol-5-yl-ethyl)-methyl-(2-pyrrolid...)
Affinity DataKi:  31nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013966((2-Benzo[1,3]dioxol-5-yl-ethyl)-methyl-(2-pyrrolid...)
Affinity DataKi:  90nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013962(2-(2H-1,3-benzodioxol-5-yl)-N-methyl-N-[(2R)-2-(py...)
Affinity DataKi:  456nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013968(2-(2-Amino-4,5-dichloro-phenyl)-N-methyl-N-(2-pyrr...)
Affinity DataKi:  523nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]bremazocine radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  1.37E+3nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  1.44E+3nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013968(2-(2-Amino-4,5-dichloro-phenyl)-N-methyl-N-(2-pyrr...)
Affinity DataKi:  1.54E+3nMAssay Description:Affinity of compound towards Dopamine receptor D2 was determined in presence of [3H](-)-sulpiride radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  1.62E+3nMAssay Description:Affinity of compound towards Sigma opioid receptor was determined in presence of [3H](+)-3-PPP radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  1.67E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  2.21E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013962(2-(2H-1,3-benzodioxol-5-yl)-N-methyl-N-[(2R)-2-(py...)
Affinity DataKi:  3.63E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003747((+)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  3.79E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013962(2-(2H-1,3-benzodioxol-5-yl)-N-methyl-N-[(2R)-2-(py...)
Affinity DataKi:  6.99E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 labeled with [3H]bremazocine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013962(2-(2H-1,3-benzodioxol-5-yl)-N-methyl-N-[(2R)-2-(py...)
Affinity DataKi:  7.21E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 labeled with [3H]bremazocine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013955(N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  7.35E+3nMAssay Description:Affinity of compound towards dopamine-D2 receptor was determined in presence of [3H](-)-sulpiride radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataIC50:  2nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013968(2-(2-Amino-4,5-dichloro-phenyl)-N-methyl-N-(2-pyrr...)
Affinity DataIC50:  12nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013971(Methyl-(2-naphthalen-2-yl-ethyl)-(2-pyrrolidin-1-y...)
Affinity DataIC50:  37nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013986(2-(2,3-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-...)
Affinity DataIC50:  42nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013961(2-(2,4-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-...)
Affinity DataIC50:  76nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013953(N-Methyl-2-naphthalen-1-yl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataIC50:  77nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013954(2-(3,4-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-...)
Affinity DataIC50:  110nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013956(Methyl-phenethyl-(2-pyrrolidin-1-yl-cyclohexyl)-am...)
Affinity DataIC50:  125nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50367953(CHEMBL607210)
Affinity DataIC50:  128nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50008848((+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...)
Affinity DataIC50:  194nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013973(2-(4-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataIC50:  196nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013979(N-Methyl-2-phenylsulfanyl-N-(2-pyrrolidin-1-yl-cyc...)
Affinity DataIC50:  200nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013959(2-(2-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataIC50:  208nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013985(2-(3-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataIC50:  211nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013981(2-(4-Chloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-...)
Affinity DataIC50:  224nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013984(2-(4-Bromo-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-c...)
Affinity DataIC50:  228nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50367954(CHEMBL607450)
Affinity DataIC50:  278nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013960(N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-(3,4,5...)
Affinity DataIC50:  302nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013982(4-(2,4-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-...)
Affinity DataIC50:  418nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013965(2-(2-Chloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-...)
Affinity DataIC50:  870nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013989(Methyl-(2-pyrrolidin-1-yl-cyclohexyl)-carbamic aci...)
Affinity DataIC50:  928nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013950(CHEMBL2374421 | N-Methyl-N-(2-pyrrolidin-1-yl-cycl...)
Affinity DataIC50:  966nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013988(N-Methyl-2-phenyl-N-(2-pyrrolidin-1-yl-cyclohexyl)...)
Affinity DataIC50:  1.16E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013972(N-Methyl-2-phenoxy-N-(2-pyrrolidin-1-yl-cyclohexyl...)
Affinity DataIC50:  1.25E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013976(N-Methyl-3-phenyl-N-(2-pyrrolidin-1-yl-cyclohexyl)...)
Affinity DataIC50:  1.34E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013991(2-(2,6-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataIC50:  1.39E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013983(N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-thioph...)
Affinity DataIC50:  1.52E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013978(N-Methyl-2-(3-nitro-phenyl)-N-(2-pyrrolidin-1-yl-c...)
Affinity DataIC50:  1.61E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013951(N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-(2H-1l...)
Affinity DataIC50:  2.10E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50013952(N-Methyl-2-(4-nitro-phenyl)-N-(2-pyrrolidin-1-yl-c...)
Affinity DataIC50:  2.37E+3nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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