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Found 32 Enz. Inhib. hit(s) with all data for entry = 50033732
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  4.53E+4nMAssay Description:Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  5.49E+4nMAssay Description:Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  6.78E+4nMAssay Description:Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50:  7.57E+4nMAssay Description:Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50:  8.39E+4nMAssay Description:Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed