Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50033682
LigandPNGBDBM50349619(CHEMBL1808977)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349632(CHEMBL1808990)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349628(CHEMBL1808986)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349621(CHEMBL1808979)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349629(CHEMBL1808987)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349622(CHEMBL1808980)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349626(CHEMBL1808984)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349619(CHEMBL1808977)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349623(CHEMBL1808981)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349630(CHEMBL1808988)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349628(CHEMBL1808986)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308767(1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349630(CHEMBL1808988)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349624(CHEMBL1808982)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349627(CHEMBL1808985)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349625(CHEMBL1808983)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349632(CHEMBL1808990)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349633(CHEMBL1808991)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349633(CHEMBL1808991)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50308767(1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349620(CHEMBL1808978)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349626(CHEMBL1808984)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349629(CHEMBL1808987)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349627(CHEMBL1808985)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349634(CHEMBL1808992)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349625(CHEMBL1808983)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349619(CHEMBL1808977)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349634(CHEMBL1808992)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349622(CHEMBL1808980)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349632(CHEMBL1808990)
Affinity DataIC50:  6nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349630(CHEMBL1808988)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349621(CHEMBL1808979)
Affinity DataIC50:  7nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349621(CHEMBL1808979)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  8nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349620(CHEMBL1808978)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308767(1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349623(CHEMBL1808981)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349626(CHEMBL1808984)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349622(CHEMBL1808980)
Affinity DataIC50:  10.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50349624(CHEMBL1808982)
Affinity DataIC50:  13.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349633(CHEMBL1808991)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349623(CHEMBL1808981)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349635(CHEMBL1808993)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349628(CHEMBL1808986)
Affinity DataIC50:  18nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349625(CHEMBL1808983)
Affinity DataIC50:  18.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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