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Found 26 Enz. Inhib. hit(s) with all data for entry = 50033831
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352142(CHEMBL1824770)
Affinity DataIC50:  69nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352145(CHEMBL1824773)
Affinity DataIC50:  134nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352143(CHEMBL1824771)
Affinity DataIC50:  155nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM82106(6,8,10-Traiazaspiro[4.5]deca-6,8-diene-7,9-diamine...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352144(CHEMBL1824772)
Affinity DataIC50:  548nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM82113(1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine...)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352146(CHEMBL1824776)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352132(CHEMBL1824519)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352133(CHEMBL1824528)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352134(CHEMBL1824529)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352135(CHEMBL1824530)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352136(CHEMBL1824531)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352137(CHEMBL1824532)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352138(CHEMBL535030)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352139(CHEMBL1824533)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352140(CHEMBL1824534)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352141(CHEMBL1824535)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352131(CHEMBL1824520)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352130(CHEMBL1824521)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352129(CHEMBL1824522)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352128(CHEMBL1824523)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352127(CHEMBL1824524)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352126(CHEMBL1824525)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352124(CHEMBL1824527)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50352125(CHEMBL1824526)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed