Found 20 Enz. Inhib. hit(s) with all data for entry = 8227 TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 2.50E+3nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.75E+3nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 5.50E+3nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 8.00E+3nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Affinity DataIC50: 8.65E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.25E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
