Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50033900
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353582(CHEMBL1831083)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353574(CHEMBL1831088)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353577(CHEMBL1831091)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353573(CHEMBL1828655)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353576(CHEMBL1831090)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353575(CHEMBL1831089)
Affinity DataIC50:  120nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353584(CHEMBL1831085)
Affinity DataIC50:  140nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353583(CHEMBL1831084)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353585(CHEMBL1831086)
Affinity DataIC50:  290nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353581(CHEMBL1831082)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  330nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353580(CHEMBL1831094)
Affinity DataIC50:  350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  350nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353586(CHEMBL1831087)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50253770(CHEMBL518482 | [4-(Imidazol-1-yl-phenyl-methyl)-ph...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50176808(5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benz...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353579(CHEMBL1831093)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  3.14E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed