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Found 88 Enz. Inhib. hit(s) with all data for entry = 50033994
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355111(CHEMBL1835210)
Affinity DataIC50:  12nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355109(CHEMBL1835209)
Affinity DataIC50:  15nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  22nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  24nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  26nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355110(CHEMBL1835208)
Affinity DataIC50:  29nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355110(CHEMBL1835208)
Affinity DataIC50:  41nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355111(CHEMBL1835210)
Affinity DataIC50:  41nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355109(CHEMBL1835209)
Affinity DataIC50:  46nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  50nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355103(CHEMBL1835399)
Affinity DataIC50:  50nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355112(CHEMBL1835211)
Affinity DataIC50:  59nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355102(CHEMBL1835325)
Affinity DataIC50:  60nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  86nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355111(CHEMBL1835210)
Affinity DataIC50:  92nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355112(CHEMBL1835211)
Affinity DataIC50:  108nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355097(CHEMBL1835320)
Affinity DataIC50:  136nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355098(CHEMBL1835321)
Affinity DataIC50:  150nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355107(CHEMBL1835403)
Affinity DataIC50:  163nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355093(CHEMBL1835316)
Affinity DataIC50:  219nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  233nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355089(CHEMBL1835212)
Affinity DataIC50:  246nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355098(CHEMBL1835321)
Affinity DataIC50:  289nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355109(CHEMBL1835209)
Affinity DataIC50:  346nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355090(CHEMBL1835313)
Affinity DataIC50:  413nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355110(CHEMBL1835208)
Affinity DataIC50:  437nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355095(CHEMBL1835318)
Affinity DataIC50:  441nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355091(CHEMBL1835314)
Affinity DataIC50:  453nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355106(CHEMBL1835402)
Affinity DataIC50:  459nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355108(CHEMBL1835404)
Affinity DataIC50:  573nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355111(CHEMBL1835210)
Affinity DataIC50:  635nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355092(CHEMBL1835315)
Affinity DataIC50:  772nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355098(CHEMBL1835321)
Affinity DataIC50:  781nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355107(CHEMBL1835403)
Affinity DataIC50:  907nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355112(CHEMBL1835211)
Affinity DataIC50:  965nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355108(CHEMBL1835404)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355109(CHEMBL1835209)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355102(CHEMBL1835325)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355096(CHEMBL1835319)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355110(CHEMBL1835208)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355112(CHEMBL1835211)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355105(CHEMBL1835401)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355104(CHEMBL1835400)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355096(CHEMBL1835319)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355103(CHEMBL1835399)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355108(CHEMBL1835404)
Affinity DataIC50:  3.11E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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