Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human CRTh2 receptor in human eosinophils assessed as inhibition of DK-PGD2-induced CD11b expressionMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 15 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 15 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of rat aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 159nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair