TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Agonist activity at human S1P1 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Agonist activity at human S1P4 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Agonist activity at human S1P2 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Agonist activity at human S1P3 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.72E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.63E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.84E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair