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Found 10 Enz. Inhib. hit(s) with all data for entry = 50034323
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  2.10nMAssay Description:Agonist activity at human S1P1 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  2.20nMAssay Description:Agonist activity at human S1P4 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  5.90nMAssay Description:Agonist activity at human S1P2 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataIC50:  23nMAssay Description:Agonist activity at human S1P3 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50360522(CHEMBL1935662)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50360521(CHEMBL1935666)
Affinity DataEC50:  2.72E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50360520(CHEMBL1935665)
Affinity DataEC50:  3.63E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50360519(CHEMBL1935664)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50158336(2-(4-octylphenethyl)-2-aminopropane-1,3-diol | 2-A...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50360518(CHEMBL1935663)
Affinity DataEC50:  2.84E+3nMAssay Description:Agonist activity at EGFP-tagged S1P1 receptor expressed in human UOS2 cells assessed as receptor internalization in endosomes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed