Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50042107
TargetAndrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420542(CHEMBL2086965)
Affinity DataIC50:  1.33E+4nMAssay Description:Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420539(CHEMBL2086966)
Affinity DataIC50:  1.59E+4nMAssay Description:Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420541(CHEMBL2086967)
Affinity DataIC50:  1.79E+4nMAssay Description:Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420542(CHEMBL2086965)
Affinity DataIC50:  2.25E+4nMAssay Description:Antagonist activity at PR assessed as inhibition of progesterone-induced fluorescent labelled SRC1-4 recruitment after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50:  2.63E+4nMAssay Description:Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50:  2.77E+4nMAssay Description:Antagonist activity at PR assessed as inhibition of progesterone-induced fluorescent labelled SRC1-4 recruitment after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERbeta complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420542(CHEMBL2086965)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERbeta complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERalpha complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled SRC1-4 from dexamethasone-GR complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420542(CHEMBL2086965)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled SRC1-4 from dexamethasone-GR complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420542(CHEMBL2086965)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERalpha complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed