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Found 13 Enz. Inhib. hit(s) with all data for entry = 50039549
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50296247(3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...)
Affinity DataKi:  6.55E+4nMAssay Description:Uncompetitive inhibition of COX2 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50296247(3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...)
Affinity DataIC50:  4.25E+4nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341139(CHEMBL1760551 | N-Sinapoyl serotonin)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50296247(3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341139(CHEMBL1760551 | N-Sinapoyl serotonin)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  1.41E+6nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank