BindingDB PrimarySearch

Found 21 Enz. Inhib. hit(s) with all data for entry = 50040059

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388692(CHEMBL2059582)

Ki: 0.794nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388689(CHEMBL2059578)

Ki: 1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388691(CHEMBL2059580)

Ki: 1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388701(CHEMBL2059584)

Ki: 1.58nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388700(CHEMBL2059577)

Ki: 2nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388693(CHEMBL2059583)

Ki: 2.51nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388697(CHEMBL2059588)

Ki: 2.51nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388695(CHEMBL2059586)

Ki: 2.51nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388694(CHEMBL2059585)

Ki: 3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388690(CHEMBL2059579)

Ki: 3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50240618((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)

Ki: 3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

ChEBI
CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388699(CHEMBL2059581)

Ki: 3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388696(CHEMBL2059587)

Ki: 7.94nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388698(CHEMBL2059590)

Ki: 10nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388687(CHEMBL538635)

Ki: 12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388702(CHEMBL2059589)

Ki: 12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388688(CHEMBL550064)

Ki: 63.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388686(CHEMBL74656)

Ki: 100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL

BDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)

EC50: 10nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase ChEBI
CHEMBL KEGG PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL

BDBM50240618((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)

EC50: 6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

ChEBI
CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL

BDBM50388698(CHEMBL2059590)

EC50: 10nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed