Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50039978
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387167(CHEMBL2047981)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387168(CHEMBL2047982)
Affinity DataIC50:  13.1nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387178(CHEMBL2047994)
Affinity DataIC50:  16.5nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387176(CHEMBL2047992)
Affinity DataIC50:  22.1nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  24.3nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387175(CHEMBL2047991)
Affinity DataIC50:  35.9nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387177(CHEMBL2047993)
Affinity DataIC50:  46.7nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387164(CHEMBL2047995)
Affinity DataIC50:  64.8nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387169(CHEMBL2047983)
Affinity DataIC50:  69.2nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387166(CHEMBL2047980)
Affinity DataIC50:  75.9nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387174(CHEMBL2047990)
Affinity DataIC50:  77.7nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387170(CHEMBL2047984)
Affinity DataIC50:  81.5nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387165(CHEMBL2047979)
Affinity DataIC50:  87.8nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387171(CHEMBL2047985)
Affinity DataIC50:  94.9nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387172(CHEMBL2047986)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Academy Of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387173(CHEMBL2047988)
Affinity DataIC50:  148nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed