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Found 8 Enz. Inhib. hit(s) with all data for entry = 50040865
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as inhibition constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataKi:  1.57E+4nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as inhibition constant for enzyme-substrate-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable linoleate 9S-lipoxygenase 5(Solanum tuberosum)
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of potato 5-lipoxygenase assessed as residual activity preincubated for 10 mins measured by real-time spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  5.19E+4nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401192(CHEMBL418973)
Affinity DataIC50:  5.54E+4nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Groningen Research Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401191(CHEMBL2206368)
Affinity DataIC50:  5.85E+4nMAssay Description:Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed