Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with all data for entry = 50040156
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50390010(CHEMBL2071516)
Affinity DataIC50:  900nMAssay Description:Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells preincubated for 10 mins measured after 1 min by RP-HPLC analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50390011(CHEMBL2071517)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells preincubated for 10 mins measured after 1 min by RP-HPLC analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50390012(CHEMBL390538)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells preincubated for 10 mins measured after 1 min by RP-HPLC analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed