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Found 11 Enz. Inhib. hit(s) with all data for entry = 50042135
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421186(CHEMBL2086800)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421184(CHEMBL2086798)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421190(CHEMBL2086805)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421187(CHEMBL2086801)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421193(CHEMBL2086802)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421189(CHEMBL2086804)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421188(CHEMBL2086803)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421191(CHEMBL2086402)
Affinity DataIC50: >100nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421192(CHEMBL2087240)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421185(CHEMBL2086799)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed