BindingDB PrimarySearch

Found 20 Enz. Inhib. hit(s) with all data for entry = 50040231

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50240618((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)

Ki: 3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

ChEBI
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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388698(CHEMBL2059590)

Ki: 10nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388687(CHEMBL538635)

Ki: 12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391074(CHEMBL2087326)

Ki: 15.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391069(TD-5108 | VELUSETRAG)

Ki: 19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391065(CHEMBL2087336)

Ki: 19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391068(CHEMBL2087334)

Ki: 19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391067(CHEMBL2087328)

Ki: 25.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391070(CHEMBL2087324)

Ki: 31.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391073(CHEMBL2087333)

Ki: 39.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391066(CHEMBL2087325)

Ki: 39.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391065(CHEMBL2087336)

Ki: 50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391064(CHEMBL2087332)

Ki: 50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391063(CHEMBL2087331)

Ki: 50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391072(CHEMBL2087327)

Ki: 50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391071(CHEMBL2087329)

Ki: 100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50388686(CHEMBL74656)

Ki: 100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL

BDBM50391062(CHEMBL2087330)

Ki: 100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL

BDBM50391069(TD-5108 | VELUSETRAG)

EC50: 12.6nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myentric plexus assessed as contractionMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

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5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL

BDBM50240618((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)

EC50: 6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myentric plexus assessed as contractionMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

ChEBI
CHEMBL PC cid PC sid Patents Similars

Details Article PubMed