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Found 24 Enz. Inhib. hit(s) with all data for entry = 50040703
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398648(CHEMBL2178104)
Affinity DataIC50:  110nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398643(CHEMBL2178105)
Affinity DataIC50:  340nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398647(CHEMBL2178106)
Affinity DataIC50:  550nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398645(CHEMBL2178108)
Affinity DataIC50:  760nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21 (DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye redu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398646(CHEMBL2178107)
Affinity DataIC50:  780nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398645(CHEMBL2178108)
Affinity DataIC50:  930nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398644(CHEMBL2177115)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398639(CHEMBL2178109)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398643(CHEMBL2178105)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21 (DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye redu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398642(CHEMBL2178110)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398641(CHEMBL1076869)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398640(CHEMBL2178111)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398639(CHEMBL2178109)
Affinity DataIC50:  4.67E+3nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21 (DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye redu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398638(CHEMBL2178112)
Affinity DataIC50:  6.06E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM69647(MLS001211237 | N-(1,3-benzothiazol-2-yl)-3-methoxy...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50:  9.48E+3nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21 (DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye redu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21 (DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye redu...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398637(CHEMBL2177491)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398636(CHEMBL2177492)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398635(CHEMBL2177493)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398634(CHEMBL2177494)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398633(CHEMBL2177495)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed