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Found 37 Enz. Inhib. hit(s) with all data for entry = 50040708
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398700(CHEMBL2178733)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398709(CHEMBL2178724)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398701(CHEMBL2178732)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398701(CHEMBL2178732)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398709(CHEMBL2178724)
Affinity DataKi:  3.30E+4nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398709(CHEMBL2178724)
Affinity DataKi:  7.40E+4nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398706(CHEMBL2178727)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398707(CHEMBL2178726)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398708(CHEMBL2178725)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398700(CHEMBL2178733)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398701(CHEMBL2178732)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398703(CHEMBL2178730)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398704(CHEMBL2178729)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398705(CHEMBL2178728)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398706(CHEMBL2178727)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398707(CHEMBL2178726)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398708(CHEMBL2178725)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398705(CHEMBL2178728)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398704(CHEMBL2178729)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398703(CHEMBL2178730)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398706(CHEMBL2178727)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398707(CHEMBL2178726)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398704(CHEMBL2178729)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398705(CHEMBL2178728)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398703(CHEMBL2178730)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398700(CHEMBL2178733)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398708(CHEMBL2178725)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  4.30nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins by cAMP EIAMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataIC50:  37nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins by cAMP EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398700(CHEMBL2178733)
Affinity DataIC50:  200nMAssay Description:Partial agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins by cAMP E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50398701(CHEMBL2178732)
Affinity DataIC50: >1.00E+5nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins by cAMP EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed