Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50001384
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015205(4-Pentadeca-1,3,6,9-tetraenylsulfanyl-butyric acid...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015209(2-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015206(4-Pentadeca-1,3-dien-6-ynylsulfanyl-butyric acid m...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015203(4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid met...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase expressed from human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50008999(5-Methyl-2-[2-(naphthalen-2-yloxy)-ethyl]-2,4-dihy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015203(4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid met...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015204(4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid | C...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015210(3-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015207(3-Pentadeca-1,3-dien-6-ynylsulfanyl-benzoic acid m...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015208(4-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50015202(4-Pentadeca-1,3-dienylsulfanyl-butyric acid methyl...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed