Affinity Data by PubMed id=23202846

PubMed code 23202846

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50489171 (CHEMBL2316337 \| acs.jmedchem.1c00409_ST.364) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of SARS coronavirus 3C-like protease pretreated for 5 mins before substrate addition by fluorimetry				Eur J Med Chem 59: 1-6 (2013) Article DOI: 10.1016/j.ejmech.2012.10.053 BindingDB Entry DOI: 10.7270/Q2K93BDN
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50489170 (CHEMBL2316336) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of SARS coronavirus 3C-like protease pretreated for 5 mins before substrate addition by fluorimetry				Eur J Med Chem 59: 1-6 (2013) Article DOI: 10.1016/j.ejmech.2012.10.053 BindingDB Entry DOI: 10.7270/Q2K93BDN
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50489169 (CHEMBL2316339) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of SARS coronavirus 3C-like protease pretreated for 5 mins before substrate addition by fluorimetry				Eur J Med Chem 59: 1-6 (2013) Article DOI: 10.1016/j.ejmech.2012.10.053 BindingDB Entry DOI: 10.7270/Q2K93BDN
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50489172 (CHEMBL2316338) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of SARS coronavirus 3C-like protease pretreated for 5 mins before substrate addition by fluorimetry				Eur J Med Chem 59: 1-6 (2013) Article DOI: 10.1016/j.ejmech.2012.10.053 BindingDB Entry DOI: 10.7270/Q2K93BDN
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%