Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50042344
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50: >1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50: >1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50: >1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50: >2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50: >2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50: >2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424347(CHEMBL2314780)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424348(CHEMBL2314791)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424350(CHEMBL2314788)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424349(CHEMBL2314789)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424351(CHEMBL2314782)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50424352(CHEMBL2314781)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed