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Found 32 Enz. Inhib. hit(s) with all data for entry = 50042369
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424952(CHEMBL2315814)
Affinity DataIC50:  14nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424951(CHEMBL2315821)
Affinity DataIC50:  17nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424950(CHEMBL2315818)
Affinity DataIC50:  53nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424949(CHEMBL2315817)
Affinity DataIC50:  74nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424948(CHEMBL2315816)
Affinity DataIC50:  77nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataIC50:  82nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424946(CHEMBL2315815)
Affinity DataIC50:  92nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataIC50:  95nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424955(CHEMBL2311582)
Affinity DataIC50:  370nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424952(CHEMBL2315814)
Affinity DataIC50:  1.05E+3nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424954(CHEMBL2315822)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424949(CHEMBL2315817)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424950(CHEMBL2315818)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424946(CHEMBL2315815)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424951(CHEMBL2315821)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424954(CHEMBL2315822)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424948(CHEMBL2315816)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424955(CHEMBL2311582)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424951(CHEMBL2315821)
Affinity DataEC50:  161nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424952(CHEMBL2315814)
Affinity DataEC50:  164nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424950(CHEMBL2315818)
Affinity DataEC50:  231nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424952(CHEMBL2315814)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424950(CHEMBL2315818)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424951(CHEMBL2315821)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed