Compile Data Set for Download or QSAR
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Found 11 Enz. Inhib. hit(s) with all data for entry = 50042999
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434370(CHEMBL593252 | GNF-Pf-3564 | Thionin (14))
Affinity DataIC50:  69nMAssay Description:Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434371(AZURE A | Azure A (12))
Affinity DataIC50:  69nMAssay Description:Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50430742(Blutene | TOLONIUM CHLORIDE | Toluidine Blue O)
Affinity DataIC50:  69nMAssay Description:Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434366(CHEMBL1789430)
Affinity DataIC50:  80nMAssay Description:Inhibition of tau protein aggregation (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM32299(2-[(2Z)-2-[(2E)-2-[[3-(2-hydroxyethyl)-5-methoxy-1...)
Affinity DataIC50:  380nMAssay Description:Inhibition of tau protein aggregation (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434368(CHEMBL2386876)
Affinity DataIC50:  970nMAssay Description:Inhibition of tau protein aggregation (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434369(METHYLENE BLUE CHLORIDE HYDRATE | Methylene Blue |...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434371(AZURE A | Azure A (12))
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434369(METHYLENE BLUE CHLORIDE HYDRATE | Methylene Blue |...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of tau protein aggregation (unknown origin) by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed