Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50035886
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  50nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50:  160nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015707(2-Amino-6-({prop-2-ynyl-[4-(2,2,2-trifluoro-acetyl...)
Affinity DataIC50:  510nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015708(2-Amino-6-{[(4-nitro-phenyl)-prop-2-ynyl-amino]-me...)
Affinity DataIC50:  620nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015702(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  640nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015701(6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-2...)
Affinity DataIC50:  770nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015697(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  1.00E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015703(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015696(6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-3...)
Affinity DataIC50:  2.40E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  7.20E+3nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015707(2-Amino-6-({prop-2-ynyl-[4-(2,2,2-trifluoro-acetyl...)
Affinity DataIC50:  1.02E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368120(CHEMBL62672)
Affinity DataIC50:  1.10E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368121(CHEMBL293442)
Affinity DataIC50:  1.13E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368123(CHEMBL64776)
Affinity DataIC50:  1.15E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015697(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  2.03E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015708(2-Amino-6-{[(4-nitro-phenyl)-prop-2-ynyl-amino]-me...)
Affinity DataIC50:  2.26E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015701(6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-2...)
Affinity DataIC50:  3.73E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015703(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  6.66E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015704(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)
Affinity DataIC50:  6.66E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015702(4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethy...)
Affinity DataIC50:  7.26E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015704(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)
Affinity DataIC50:  9.60E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015696(6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-3...)
Affinity DataIC50:  1.00E+5nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368122(CHEMBL62419)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed