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Found 33 Enz. Inhib. hit(s) with all data for entry = 50043066
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435417(CHEMBL2391912)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435416(CHEMBL2391780)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435415(CHEMBL2391779)
Affinity DataIC50:  74nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM61946(3-keto-N-phenyl-1,2-benzothiazole-2-carboxamide | ...)
Affinity DataIC50:  76nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435414(CHEMBL2391777)
Affinity DataIC50:  85nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM61945(3-oxidanylidene-N-(phenylmethyl)-1,2-benzothiazole...)
Affinity DataIC50:  86nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435413(CHEMBL2391778)
Affinity DataIC50:  88nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435412(CHEMBL2391911)
Affinity DataIC50:  115nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435411(CHEMBL2391781)
Affinity DataIC50:  206nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435410(CHEMBL2391910)
Affinity DataIC50:  241nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435409(CHEMBL2391772)
Affinity DataIC50:  438nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM34737(2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...)
Affinity DataIC50:  466nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM44439(2-(3-pyrrolidin-1-ylquinoxalin-2-yl)-2-thiophen-2-...)
Affinity DataIC50:  533nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435408(CHEMBL2391773)
Affinity DataIC50:  593nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435407(CHEMBL2391918)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435406(CHEMBL2391922)
Affinity DataIC50:  3.07E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435405(CHEMBL2391917)
Affinity DataIC50:  4.17E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435404(CHEMBL2391920)
Affinity DataIC50:  8.09E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435403(CHEMBL2391921)
Affinity DataIC50:  9.63E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435402(CHEMBL2391774)
Affinity DataIC50:  9.82E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435401(CHEMBL2391919)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435400(CHEMBL99313 | acs.jmedchem.1c00409_ST.173)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435399(CHEMBL2391914)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435398(CHEMBL2391915)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435397(CHEMBL2391923)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435395(CHEMBL2391776)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435394(CHEMBL2391913 | acs.jmedchem.1c00409_ST.171)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM61908(2-methyl-1,2-benzothiazol-3-one | KUC103657N | acs...)
Affinity DataIC50:  4.24E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM46658(1,2-benzothiazol-3-one | MLS-0254244.0001 | US9011...)
Affinity DataIC50:  4.67E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435393(CHEMBL1996492)
Affinity DataIC50:  9.12E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435392(CHEMBL2391775)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed