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Found 27 Enz. Inhib. hit(s) with all data for entry = 50001495
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015924(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015916(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015900(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015922(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015913(Acetic acid 2-(benzyl-methyl-carbamoyl)-7-methoxy-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015904(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015912(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015907(CHEMBL432765 | [(3-Acetoxymethyl-7-methoxy-5,5,8-t...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015921(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015920(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015919(4-[(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015909(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015914((6R,7S)-3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5la...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015901(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015915(4-{[((6R,7S)-3-Acetoxymethyl-7-methoxy-5,5,8-triox...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015923(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015918(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015910(Acetic acid 2-tert-butylcarbamoyl-7-methoxy-5,5,8-...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015917(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015879(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015902(3-[(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015905(Acetic acid 2-dimethylcarbamoyl-7-methoxy-5,5,8-tr...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015906(Acetic acid 2-benzylcarbamoyl-7-methoxy-5,5,8-trio...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015903(CHEMBL306251 | [((6R,7S)-3-Acetoxymethyl-7-methoxy...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015908(CHEMBL312438 | [(3-Acetoxymethyl-7-methoxy-5,5,8-t...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015899(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015911(3-[(3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed