Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50043829
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50385806(CHEMBL2041193)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50385806(CHEMBL2041193)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PHD1 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446893(CHEMBL3115307)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446888(CHEMBL3115311)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446885(CHEMBL3115276)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446884(CHEMBL3115282)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446882(CHEMBL3115284)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446883(CHEMBL3115283)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446902(CHEMBL3115294)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446903(CHEMBL3115293)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446906(CHEMBL3115290)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446887(CHEMBL3115295)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446907(CHEMBL3115289)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446901(CHEMBL3115296)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446904(CHEMBL3115292)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446905(CHEMBL3115291)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446897(CHEMBL3115302)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50385806(CHEMBL2041193)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PHD3 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446896(CHEMBL3115305)
Affinity DataIC50:  3nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446898(CHEMBL3115300)
Affinity DataIC50:  3nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446892(CHEMBL3115313)
Affinity DataIC50:  8nMAssay Description:Inhibition of PHD2 (181 to 417) (unknown origin) using HIF-1alpha peptide as substrate assessed as 2-Oxoglutarate conversion to succinic acid by beta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005351(CHEMBL3115308)
Affinity DataIC50: <10nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005349(CHEMBL3115310)
Affinity DataIC50: <10nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005350(CHEMBL3115309)
Affinity DataIC50: <10nMAssay Description:Inhibition of FLAG-tagged full length PHD2 (unknown origin) expressed in Sf9 cells using HIF-1alpha peptide as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50431018(CHEMBL2338326)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50431018(CHEMBL2338326)
Affinity DataIC50:  17nMAssay Description:Inhibition of full length human recombinant EGLN-3 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446886(CHEMBL3115281)
Affinity DataIC50:  20nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446895(CHEMBL3115299)
Affinity DataIC50:  46nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by [14...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446891(CHEMBL3115314 | US10246442, Example 61 | US1097506...)
Affinity DataIC50:  50nMAssay Description:Inhibition of PHD2 (181 to 417) (unknown origin) using HIF-1alpha peptide as substrate assessed as 2-Oxoglutarate conversion to succinic acid preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005346(CHEMBL3115301)
Affinity DataIC50: <50nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446894(CHEMBL3115306)
Affinity DataIC50:  65nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by [14...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446889(CHEMBL3115316)
Affinity DataIC50:  100nMAssay Description:Inhibition of human PHD2 expressed in Sf9 cells using HIF-1alpha peptide as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446900(CHEMBL3115312)
Affinity DataIC50:  100nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005344(CHEMBL3115303)
Affinity DataIC50: <100nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50005345(CHEMBL3115304)
Affinity DataIC50: <100nMAssay Description:Inhibition of PHD2 (unknown origin) using P564 HIFlalpha as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50370833(CHEMBL221970)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446138(CHEMBL3108881)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of 6xHis-tagged VHL (unknown origin) expressed in Escherichia coli BL21 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50370811(CHEMBL441860)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM102348(US10562854, No. A41 | US8536181, A41 | US9278930, ...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446899(CHEMBL3115297)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of full length human recombinant EGLN-3 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446899(CHEMBL3115297)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446883(CHEMBL3115283)
Affinity DataEC50:  400nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446882(CHEMBL3115284)
Affinity DataEC50:  400nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446881(CHEMBL3115285)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446880(CHEMBL3115286)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446879(CHEMBL3115287)
Affinity DataEC50:  1nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446878(CHEMBL3115288)
Affinity DataEC50:  1nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446901(CHEMBL3115296)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446906(CHEMBL3115290)
Affinity DataEC50:  100nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446903(CHEMBL3115293)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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