Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50043805
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446561(CHEMBL3110215)
Affinity DataIC50:  1.10E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446559(CHEMBL3110213)
Affinity DataIC50:  4.90E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446560(CHEMBL3110214)
Affinity DataIC50:  5.10E+4nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446558(CHEMBL3110195)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50324670(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446557(CHEMBL3110204)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50446562(CHEMBL3110216)
Affinity DataIC50:  3.00E+5nMAssay Description:Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed