Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50035668
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50044994(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016403(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016410(2,6,9,11,13,14-hexahydroxy-11-(2-hydroxy-1-methyle...)
Affinity DataIC50:  41nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016413(18-HYDROXYRYANODINE | 2,6,9,11,13,14-hexahydroxy-1...)
Affinity DataIC50:  88nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016418(10-KETORYANODINE | 6,9,11,13,14-pentahydroxy-11-is...)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016416(10-ACETYLRYANODINE | 6,9,11,13,14-pentahydroxy-11-...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016411(2',6',9',11',13',14'-hexahydroxy-11'-isopropyl-7',...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016406(2,6,11,13,14-pentahydroxy-11-isopropyl-9-methoxy-3...)
Affinity DataIC50:  280nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016417(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  310nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016405(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  860nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016412(2,11,13,14-tetrahydroxy-11-isopropyl-6,9-dimethoxy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016409(2,6,11,14-tetrahydroxy-11-isopropyl-9,13-dimethoxy...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016404(2,3,6,9,11,13,14-heptahydroxy-3-hydroxymethyl-11-i...)
Affinity DataIC50:  4.90E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016414(6,9,11,13,14-pentahydroxy-11-isopropyl-3,7,10-trim...)
Affinity DataIC50:  7.30E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016402(11-isopropyl-7,10-dimethyl-3-methylene-(1R,2R,6S,7...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016420(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016408(2,6,8,12-tetrahydroxy-10-isopropyl-3,7,11-trimethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016407(6,11,14-trihydroxy-11-isopropyl-2,9,13-trimethoxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016415(11-isopropyl-3,7,10-trimethyl-(1R,2R,3S,6S,7S,9S,1...)
Affinity DataIC50:  3.50E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed