Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50043972
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Yerevan State University

Curated by ChEMBL
LigandPNGBDBM50449237(CHEMBL3128141)
Affinity DataIC50:  600nMAssay Description:Inhibition of 20s immunoproteasome beta 1 subunit caspase-like activity in human blood monocytes using Z-LLE-betaNA as substrate at 2 uM preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Yerevan State University

Curated by ChEMBL
LigandPNGBDBM50449238(CHEMBL3128248)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of 20s immunoproteasome beta 2 subunit trypsin-like activity in human blood monocytes using Boc-LRR-AMC as substrate preincubated for 2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Yerevan State University

Curated by ChEMBL
LigandPNGBDBM50449237(CHEMBL3128141)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of 20s proteasome beta 1 subunit caspase-like activity in human HeLa cells using Z-nLPnLD as substrate after 17 hrs by chemiluminescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed