BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with all data for entry = 50044327

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Washington University

Curated by ChEMBL

BDBM31592(PF-2545920 | US9138494, MP-10 | substituted pyraz...)

IC50: 1.30nMAssay Description:Inhibition of full-length human recombinant PDE10A using cyclic AMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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PDB

3D Structure (crystal)

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Washington University

Curated by ChEMBL

BDBM14754(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)

IC50: 36nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
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Details Article PubMed DrugBank
PDB

3D Structure (crystal)