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Found 44 Enz. Inhib. hit(s) with all data for entry = 50033070
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339102((5-(aminomethyl)-4-(2,4-dichlorophenyl)-6-methylpy...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339100(5-(aminomethyl)-4-(2,4-dichlorophenyl)-6-methylpic...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229666((2S,3S)-2-((S)-1-((2S,3S)-2-amino-3-methylpentanoy...)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339101(5-(aminomethyl)-4-(2,4-dichlorophenyl)-N,6-dimethy...)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339103(5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyri...)
Affinity DataKi:  6.60E+4nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339095(5-(aminomethyl)-N-cyclopropyl-4-(4-fluorophenyl)-6...)
Affinity DataKi:  1.06E+5nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339096((5-(aminomethyl)-4-(4-fluorophenyl)-6-methylpyridi...)
Affinity DataKi:  1.37E+5nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339099(5-(aminomethyl)-4-(2,4-difluorophenyl)-6-methyl-N-...)
Affinity DataKi:  1.79E+5nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339098(5-(aminomethyl)-N-cyclopropyl-4-(2,4-difluoropheny...)
Affinity DataKi:  1.82E+5nMAssay Description:Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339101(5-(aminomethyl)-4-(2,4-dichlorophenyl)-N,6-dimethy...)
Affinity DataIC50:  6nMAssay Description:Competitive inhibition of human recombinant DPP4 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339103(5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyri...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339101(5-(aminomethyl)-4-(2,4-dichlorophenyl)-N,6-dimethy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339100(5-(aminomethyl)-4-(2,4-dichlorophenyl)-6-methylpic...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339102((5-(aminomethyl)-4-(2,4-dichlorophenyl)-6-methylpy...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339095(5-(aminomethyl)-N-cyclopropyl-4-(4-fluorophenyl)-6...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339098(5-(aminomethyl)-N-cyclopropyl-4-(2,4-difluoropheny...)
Affinity DataIC50:  674nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339099(5-(aminomethyl)-4-(2,4-difluorophenyl)-6-methyl-N-...)
Affinity DataIC50:  674nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339096((5-(aminomethyl)-4-(4-fluorophenyl)-6-methylpyridi...)
Affinity DataIC50:  686nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339097(CHEMBL1688418 | ethyl 1-(5-(aminomethyl)-4-(4-fluo...)
Affinity DataIC50:  937nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229666((2S,3S)-2-((S)-1-((2S,3S)-2-amino-3-methylpentanoy...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339123(3-(aminomethyl)-N-cyclopropyl-6-(4-methoxyphenyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339124((3-(aminomethyl)-6-(4-methoxyphenyl)-2-methylpyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339125((3-(aminomethyl)-6-(4-methoxyphenyl)-2-methylpyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339122((3-(aminomethyl)-6-(2,4-dichlorophenyl)-2-methylpy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339121((3-(aminomethyl)-6-(2,4-dichlorophenyl)-2-methylpy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339120(3-(aminomethyl)-N-cyclopropyl-6-(2,4-dichloropheny...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339119(CHEMBL1688522 | ethyl 1-(3-(aminomethyl)-6-(4-chlo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339118((3-(aminomethyl)-6-(4-chlorophenyl)-2-methylpyridi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339117((3-(aminomethyl)-6-(4-chlorophenyl)-2-methylpyridi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339116((3-(aminomethyl)-6-(4-fluorophenyl)-2-methylpyridi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339115(6-(aminomethyl)-4-(4-methoxyphenyl)-2-methylnicoti...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339114(6-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methylnic...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339113(6-(aminomethyl)-4-(4-chlorophenyl)-2-methylnicotin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339112(6-(aminomethyl)-4-(2-fluorophenyl)-2-methylnicotin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339111(5-(aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339110((5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylpyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339109((R)-(5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylp...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339108(5-(aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(5-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339107(5-(aminomethyl)-N-(3,4-dichlorobenzyl)-4-(4-methox...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339106((5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylpyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339105((5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylpyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339104(5-(aminomethyl)-N-cyclopropyl-4-(4-methoxyphenyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339093(5-cyano-4-(2,4-dichlorophenyl)-6-methylpicolinamid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339094(5-cyano-4-(2,4-dichlorophenyl)-N,6-dimethylpicolin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed