Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50032827
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  14nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  23nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335498(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  34nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335499(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  61nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335497(4-(4-(Thiiranylmethylsulfonyl)phenoxy)-phenylethan...)
Affinity DataKi:  70nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  90nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  110nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  150nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335498(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  240nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  240nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335501(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-1-sul...)
Affinity DataKi:  280nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335497(4-(4-(Thiiranylmethylsulfonyl)phenoxy)-phenylethan...)
Affinity DataKi:  330nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335497(4-(4-(Thiiranylmethylsulfonyl)phenoxy)-phenylethan...)
Affinity DataKi:  360nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335499(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  380nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  390nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  480nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335498(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  520nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335499(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ...)
Affinity DataKi:  790nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335501(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-1-sul...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335501(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-1-sul...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335501(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-1-sul...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  9.60E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  2.06E+5nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed