Compile Data Set for Download or QSAR
maximum 50k data
Found 87 Enz. Inhib. hit(s) with all data for entry = 50040818
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50:  1nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of KIT phosphorylation in human H526 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50:  2nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50:  2nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of M-CSF-induced FK506 -fussed CSF1R phosphorylation expressed in HEK293 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of KIT phosphorylation in human H526 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50:  8nMAssay Description:Inhibition of KIT phosphorylation in human H526 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50:  10.5nMAssay Description:Inhibition of M-CSF-induced FK506 -fussed CSF1R phosphorylation expressed in HEK293 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50:  15nMAssay Description:Inhibition of M-CSF-induced FK506 -fussed CSF1R phosphorylation expressed in HEK293 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400609(CHEMBL2203433)
Affinity DataIC50:  35.7nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400614(CHEMBL2203426)
Affinity DataIC50:  37nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50:  41nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50:  46.3nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50:  50.4nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)
Affinity DataIC50:  53nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400613(CHEMBL2203429)
Affinity DataIC50:  63.9nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400606(CHEMBL2203437)
Affinity DataIC50:  64.4nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400604(CHEMBL2203427)
Affinity DataIC50:  67.4nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataIC50:  74.7nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400608(CHEMBL2203435)
Affinity DataIC50:  78nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400603(CHEMBL2203428)
Affinity DataIC50:  109nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400611(CHEMBL2203431)
Affinity DataIC50:  145nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400605(CHEMBL2203438)
Affinity DataIC50:  150nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400607(CHEMBL2203436)
Affinity DataIC50:  169nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400612(CHEMBL2203430)
Affinity DataIC50:  223nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50400610(CHEMBL2203432)
Affinity DataIC50:  296nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to PDGFRalpha expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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