Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50006058
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496623(CHEMBL3134498)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of gamma-secretase (unknown origin) using Notch1 substrate assessed as Notch1-NICD productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496623(CHEMBL3134498)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of gamma-secretase (unknown origin) using APP substrate assessed as amyloid-beta40 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496624(CHEMBL3134497)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of gamma-secretase (unknown origin) using APP substrate assessed as amyloid-beta40 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496624(CHEMBL3134497)
Affinity DataIC50:  1nMAssay Description:Inhibition of gamma-secretase (unknown origin) using Notch1 substrate assessed as Notch1-NICD productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496624(CHEMBL3134497)
Affinity DataIC50:  20nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in CHO cells transfected with APP assessed as amyloid-beta42 production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50496623(CHEMBL3134498)
Affinity DataIC50:  28nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in CHO cells transfected with APP assessed as amyloid-beta42 production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed