Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50044702
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026641(CHEMBL3335367)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026642(CHEMBL3335368)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026629(CHEMBL3334509)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed