Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 50044719
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataIC50:  102nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  210nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  250nMAssay Description:Inhibition of RET C634R mutant (unknown origin) expressed in rat RAT1 cells assessed as reduction in Tyr905 phosphorylation at 0.5 to 10 uM incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  250nMAssay Description:Inhibition of RET C634R mutant (unknown origin) expressed in rat RAT1 cells assessed as reduction in Tyr1062 phosphorylation at 0.5 to 10 uM incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  380nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 20 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  420nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 3 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027457(CHEMBL3329397)
Affinity DataIC50:  440nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 0 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027456(CHEMBL3329404)
Affinity DataIC50:  750nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027456(CHEMBL3329404)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of RET C634R mutant (unknown origin) expressed in rat RAT1 cells assessed as reduction in Tyr1062 phosphorylation at 0.5 to 10 uM incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027456(CHEMBL3329404)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of RET C634R mutant (unknown origin) expressed in rat RAT1 cells assessed as reduction in Tyr905 phosphorylation at 0.5 to 10 uM incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027458(CHEMBL3329403)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027459(CHEMBL3329402)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027464(CHEMBL3329396)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027460(CHEMBL3329401)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027465(CHEMBL3329395)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027461(CHEMBL3329400)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027462(CHEMBL3329399)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027463(CHEMBL3329398)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027466(CHEMBL3329394)
Affinity DataIC50:  6.78E+4nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027467(CHEMBL3329393)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027468(CHEMBL3329392)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50027469(CHEMBL3329391)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed