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Found 108 Enz. Inhib. hit(s) with all data for entry = 50044862
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033168(CHEMBL3357106)
Affinity DataIC50:  90nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033167(CHEMBL3357105)
Affinity DataIC50:  120nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033170(CHEMBL3357108)
Affinity DataIC50:  300nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033166(CHEMBL3357104)
Affinity DataIC50:  360nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50:  360nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033167(CHEMBL3357105)
Affinity DataIC50:  450nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033173(CHEMBL3357111)
Affinity DataIC50:  470nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033166(CHEMBL3357104)
Affinity DataIC50:  480nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033281(CHEMBL3357099)
Affinity DataIC50:  780nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033281(CHEMBL3357099)
Affinity DataIC50:  950nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033178(CHEMBL3357116)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033283(CHEMBL3357097)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033176(CHEMBL3357114)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033272(CHEMBL3357124)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033168(CHEMBL3357106)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033271(CHEMBL3357123)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033180(CHEMBL3357118)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033179(CHEMBL3357117)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033269(CHEMBL3357121)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033281(CHEMBL3357099)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033166(CHEMBL3357104)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033168(CHEMBL3357106)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033276(CHEMBL1470821)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033177(CHEMBL3357115)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033175(CHEMBL3357113)
Affinity DataIC50:  9.75E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033250(CHEMBL3357120)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033361(CHEMBL3357091)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033360(CHEMBL3357092)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033359(CHEMBL3357093)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033358(CHEMBL3357094)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033356(CHEMBL3357096)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033283(CHEMBL3357097)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033282(CHEMBL3357098)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033281(CHEMBL3357099)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033280(CHEMBL3357100)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033279(CHEMBL3357101)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033278(CHEMBL3357102)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033166(CHEMBL3357104)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033168(CHEMBL3357106)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033169(CHEMBL3357107)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033170(CHEMBL3357108)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033171(CHEMBL3357109)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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