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Found 8 Enz. Inhib. hit(s) with all data for entry = 50045955
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088534(CHEMBL3576929 | US10189805, Compound 5)
Affinity DataIC50:  3.12E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088535(CHEMBL3576928 | US10189805, Compound 4)
Affinity DataIC50:  4.36E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088536(CHEMBL3576927 | US10189805, Compound 3)
Affinity DataIC50:  6.64E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088531(CHEMBL3576943 | US10189805, Compound 19)
Affinity DataIC50:  6.77E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088530(CHEMBL3576944 | US10189805, Compound 20)
Affinity DataIC50:  6.97E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088533(CHEMBL3576936 | US10189805, Compound 12)
Affinity DataIC50:  7.76E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088532(CHEMBL3576940 | US10189805, Compound 16)
Affinity DataIC50:  8.32E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  9.54E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed