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Found 178 Enz. Inhib. hit(s) with all data for entry = 50045688
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  200nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  200nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end direc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end directed cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  400nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  400nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  400nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075206(CHEMBL3414870)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075216(CHEMBL3414859)
Affinity DataIC50:  500nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  500nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  500nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM33410(CHEMBL16755 | N-hydroxyisoquinolinedione, 2)
Affinity DataIC50:  500nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075207(CHEMBL3414871)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  600nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075213(CHEMBL3414864)
Affinity DataIC50:  600nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM33410(CHEMBL16755 | N-hydroxyisoquinolinedione, 2)
Affinity DataIC50:  600nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075219(CHEMBL3414866)
Affinity DataIC50:  700nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075221(CHEMBL3414873)
Affinity DataIC50:  700nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075295(CHEMBL3414875)
Affinity DataIC50:  700nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  700nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075206(CHEMBL3414870)
Affinity DataIC50:  700nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  700nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  750nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end direc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075213(CHEMBL3414864)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075216(CHEMBL3414859)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  800nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075206(CHEMBL3414870)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075221(CHEMBL3414873)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075213(CHEMBL3414864)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075215(CHEMBL3414858)
Affinity DataIC50:  900nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075213(CHEMBL3414864)
Affinity DataIC50:  900nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075209(CHEMBL3414865)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075205(CHEMBL3414869)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075218(CHEMBL3414863)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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