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PubMed code 25864491

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 9


(Homo sapiens (Human))
BDBM50078631
PNG
(CHEMBL4650212)
Show SMILES CC(C)CS(=O)(=O)N[C@@H]1CCC(=O)N([C@H]1c1ccc(Cl)cc1)c1ccc2c(C)cc(=O)n(C)c2c1
Show InChI InChI=1S/C20H17N7/c1-15-13-27(25-24-15)11-10-26-14-23-19(17-6-8-22-9-7-17)20(26)18-4-2-16(12-21)3-5-18/h2-9,13-14H,10-11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 189n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human BRPF1 (627 to 740 residues) expressed in Escherichia coli BL21 after 1 hr by BROMOscan assay


Angew Chem Int Ed Engl 54: 6217-21 (2015)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 9


(Homo sapiens (Human))
BDBM50078631
PNG
(CHEMBL4650212)
Show SMILES CC(C)CS(=O)(=O)N[C@@H]1CCC(=O)N([C@H]1c1ccc(Cl)cc1)c1ccc2c(C)cc(=O)n(C)c2c1
Show InChI InChI=1S/C20H17N7/c1-15-13-27(25-24-15)11-10-26-14-23-19(17-6-8-22-9-7-17)20(26)18-4-2-16(12-21)3-5-18/h2-9,13-14H,10-11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.96E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human BRPF1 (627 to 740 residues) expressed in Escherichia coli BL21 after 1 hr by BROMOscan assay


Angew Chem Int Ed Engl 54: 6217-21 (2015)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%