Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50046070
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093525(taiwaniaflavone)
Affinity DataKi:  4.50E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50259862(13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...)
Affinity DataKi:  4.60E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataKi:  6.40E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50323212(6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydro...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50129952(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093524(CHEMBL3585680)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50323213(CHEMBL1208973 | cupressuflavone)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataKi:  1.45E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50:  4.50E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50259862(13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...)
Affinity DataIC50:  4.50E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093525(taiwaniaflavone)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50323212(6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydro...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50129952(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50323213(CHEMBL1208973 | cupressuflavone)
Affinity DataIC50:  9.60E+3nMAssay Description:Competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093524(CHEMBL3585680)
Affinity DataIC50:  9.80E+3nMAssay Description:Uncompetitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataIC50:  1.32E+4nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed